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Providing cutting-edge scholarly communications to worldwide, enabling them to utilize available resources effectively. We aim to bring about a change in modern scholarly communications through the effective use of editorial and publishing polices. John Ionescu Alexandru Tudor Constantinescu. Gretchen D. Journal of Translational Science is a multidisciplinary online universal Journal that distributes peer surveyed articles under open access demonstrate and a rapid publication process. Translational Science aims to translate findings in fundamental research into medical and clinical practice and meaningful health outcomes.
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This executive summary reviews the topics covered in the PDQ summary on the genetics of colorectal cancer CRC , with hyperlinks to detailed sections below that describe the evidence on each topic. At least three validated computer models are available to estimate the probability that an individual affected with cancer carries a pathogenic variant in a mismatch repair MMR gene associated with Lynch syndrome, the most common inherited CRC syndrome. Individuals with a quantified risk of 2. Many of these syndromes are also associated with extracolonic cancers and other manifestations. Serrated polyposis syndrome , which is characterized by the appearance of hyperplastic polyps, appears to have a familial component, but the genetic basis remains unknown. The natural history of some of these syndromes is still being described.
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